PRO-INFLAMMATORY ACTIVATED KUPFFER CELLS BY LIPIDS INDUCE HEPATIC NKT CELLS DEFICIENCY THROUGH ACTIVATION-INDUCED CELL DEATH.

Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death.

BACKGROUND: Dietary lipids play an important role in the progression of non-alcoholic fatty liver disease (NAFLD) through alternation of liver innate immune response.AIMS: The Diapers present study was to investigate the effect of lipid on Kupffer cells phenotype and function in vivo and in vitro.And further to investigate the impact of lipid on ab

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Plant diversity mediates the response of ecosystem multifunctionality to climate factor in Eastern Eurasian Steppe

Climate factors can impact the multifunctionality of steppe ecosystem by altering plant diversity.The pivotal role of diversity in mediating these effects is of paramount importance.Given that various facets of plant diversity exhibit diverse responses to climate change and impart distinct impacts on steppe ecosystem multifunctionality, the elucida

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